Effect of elevated atmospheric pressure on antibiotic susceptibility of Staphylococcus aureus and Streptococcus pyogenes.
نویسنده
چکیده
Staphylococcus aureus showed decreased susceptibility to penicillin, vancomycin, sodium cephalothin, and tetracycline, but increased susceptibility to sodium colistimethate, at a pressure of 68 atm in helium or helium-oxygen gas. Susceptibility of Streptococcus pyogenes was unchanged by pressurization.
منابع مشابه
Effect of elevated atmospheric pressure on penicillin binding by Staphylococcus aureus and Streptococcus pyogenes.
A gas pressure of 68 atm, elicited by helium-oxygen gas mixtures, reduced the susceptibility to penicillin of Staphylococcus aureus but not of Streptococcus pyogenes. The elevated pressure also caused a reduction in the binding of (14)C-penicillin to S. aureus, but not to S. pyogenes. When these studies were extended to glycine incorporation, it was shown that, even without penicillin, pressuri...
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 1 6 شماره
صفحات -
تاریخ انتشار 1972